In clients presently acquiring an opioid analgesic, prescribe a decreased Original dose of XANAX than indicated during the absence of an opioid and titrate according to scientific reaction. If an opioid is initiated in the affected individual previously taking XANAX, prescribe a decrease Original dose in the opioid and titrate based upon medical response.
The concomitant use of benzodiazepines and opioids enhances the risk of respiratory despair as a result of actions at various receptor web sites in the CNS that Regulate respiration.
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Human Info Revealed knowledge from observational experiments on using benzodiazepines during pregnancy usually do not report a clear Affiliation with benzodiazepines and important start defects. Although early research described an increased possibility of congenital malformations with diazepam and chlordiazepoxide, there was no steady sample pointed out.
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